Literatur

Literaturliste

Es gibt eine Vielzahl von wissenschaftlichen Studien von Universitäten, renommierten Instituten und Wissenschaftlern, die die positiven Effekte von Bioaktiven Kollagenpeptiden belegen. Eine Auswahl haben wir hier zusammengetragen:

  1. Tacke, S.; Gollwitzer, A.; Grammel, L.; Henke, J. Pain therapy in small pets. Tierarztliche Praxis. Ausgabe K Kleintiere/Heimtiere
    2017, 45, 53–60, doi:10.15654/TPK-161188.
  2. Bockstahler, B.; Levine, D.; Millis, D.L.; Wandrey, S.O.N. Essential Facts of Physiotherapy in Dogs and Cats; BE VetVerlag: Babenhausen, Germany, 2004.
  3. Benavente, M.; Arias, S.; Moreno, L.; Martínez, J. Production of Glucosamine Hydrochloride from Crustacean Shell. J. Pharm.
    Pharmacol. 2015, 3, 20–26, doi:10.17265/2328-2150/2015.01.003.
  4. Siebert, H.C.; Burg-Roderfeld, M.; Eckert, T.; Stötzel, S.; Kirch, U.; Diercks, T.; Humphries, M.J.; Frank, M.; Wechselberger, R.;
    Tajkhorshid, E.; et al. Interaction of the alpha2A domain of integrin with small collagen fragments. Protein Cell 2010, 1, 393–405,
    doi:10.1007/s13238-010-0038-6.
  5. Krylov, V.B.; Grachev, A.A.; Ustyuzhanina, N.E.; Ushakova, N.A.; Preobrazhenskaya, M.E.; Kozlova, N.I.; Portsel, M.N.;
    Konovalova, I.N.; Novikov, V.Y.; Siebert, H.C.; et al. Preliminary structural characterization, anti-inflammatory and
    Mar. Drugs 2021, 19, 542 28 of 30
    anticoagulant activities of chondroitin sulfates from marine fish cartilage. Russian Chem. Bull. 2011, 60, 746–753,
    doi:10.1007/s11172-011-0115-x.
  6. Burg-Roderfeld, M.; Eckert, T.; Siebert, H.C. Bioaktive Kollagenfragmente. Neue struktur-biologische Studien an KollagenIntegrin-Komplexen belegen Justus Liebigs wegweisende Ideen. Spiegel der Forschung 2011, 28, 36–43.
  7. Stötzel, S.; Schurink, M.; Wienk, H.; Siebler, U.; Burg-Roderfeld, M.; Eckert, T.; Kulik, B.; Wechselberger, R.; Sewing, J.;
    Steinmeyer, J.; et al. Molecular organization of various collagen fragments as revealed by atomic force microscopy and diffusionordered NMR spectroscopy. ChemPhysChem 2012, 13, 3117–3125, doi:10.1002/cphc.201200284.
  8. Schadow, S.; Simons, V.S.; Lochnit, G.; Kordelle, J.; Gazova, Z.; Siebert, H.C.; Steinmeyer, J. Metabolic Response of Human
    Osteoarthritic Cartilage to Biochemically Characterized Collagen Hydrolysates. Int. J. Mol. Sci. 2017, 18, 207,
    doi:10.3390/ijms18010207.
  9. Schadow, S.; Siebert, H.C.; Lochnit, G.; Kordelle, J.; Rickert, M.; Steinmeyer, J. Collagen metabolism of human osteoarthritic
    articular cartilage as modulated by bovine collagen hydrolysates. PLoS ONE 2013, 8, e53955, doi:10.1371/journal.pone.0053955.
  10. Raabe, O.; Reich, C.; Wenisch, S.; Hild, A.; Burg-Roderfeld, M.; Siebert, H.C.; Arnhold, S. Hydrolyzed fish collagen induced
    chondrogenic differentiation of equine adipose tissue-derived stromal cells. Histochem Cell Biol. 2010, 134, 545–554,
    doi:10.1007/s00418-010-0760-4.
  11.  Bertini, I.; Calderone, V.; Cosenza, M.; Fragai, M.; Lee, Y.M.; Luchinat, C.; Mangani, S.; Terni, B.; Turano, P. Conformational
    variability of matrix metalloproteinases: Beyond a single 3D structure. Proc. Natl. Acad. Sci. USA 2005, 102, 5334–5339,
    doi:10.1073/pnas.0407106102.
  12.  Mosyak, L.; Georgiadis, K.; Shane, T.; Svenson, K.; Hebert, T.; McDonagh, T.; Mackie, S.; Olland, S.; Lin, L.; Zhong, X.; et al.
    Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS-5. Protein Sci. Publ. Protein Soc.
    2008, 17, 16–21, doi:10.1110/ps.073287008.
  13. Alcaraz, L.A.; Banci, L.; Bertini, I.; Cantini, F.; Donaire, A.; Gonnelli, L. Matrix metalloproteinase-inhibitor interaction: The
    solution structure of the catalytic domain of human matrix metalloproteinase-3 with different inhibitors. J. Biol. Inorg. Chem.
    JBIC Publ. Soc. Biol. Inorg. Chem. 2007, 12, 1197–1206, doi:10.1007/s00775-007-0288-9.
  14. Sadowski, T.; Steinmeyer, J. Effects of tetracyclines on the production of matrix metalloproteinases and plasminogen activators
    as well as of their natural inhibitors, tissue inhibitor of metalloproteinases-1 and plasminogen activator inhibitor-1. Inflamm. Res.
    2001, 50, 175–182, doi:10.1007/s000110050742.
  15. Masuyer, G.; Schwager, S.L.; Sturrock, E.D.; Isaac, R.E.; Acharya, K.R. Molecular recognition and regulation of human
    angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides. Sci. Rep. 2012, 2, 717, doi:10.1038/srep00717.
  16. Kawakami, Y.; Matsuo, K.; Murata, M.; Yudoh, K.; Nakamura, H.; Shimizu, H.; Beppu, M.; Inaba, Y.; Saito, T.; Kato, T.; et al.
    Expression of Angiotensin II Receptor-1 in Human Articular Chondrocytes. Arthritis 2012, 2012, 648537, doi:10.1155/2012/648537.
  17. Nakamura, F.; Tsukamoto, I.; Inoue, S.; Hashimoto, K.; Akagi, M. Cyclic compressive loading activates angiotensin II type 1
    receptor in articular chondrocytes and stimulates hypertrophic differentiation through a G-protein-dependent pathway. FEBS
    Open Bio 2018, 8, 962–973, doi:10.1002/2211-5463.12438.
  18. Kouguchi, T.; Ohmori, T.; Shimizu, M.; Takahata, Y.; Maeyama, Y.; Suzuki, T.; Morimatsu, F.; Tanabe, S. Effects of a chicken
    collagen hydrolysate on the circulation system in subjects with mild hypertension or high-normal blood pressure. Biosci.
    Biotechnol. Biochem. 2013, 77, 691–696, doi:10.1271/bbb.120718.
  19. Kosinska, M.K.; Ludwig, T.E.; Liebisch, G.; Zhang, R.; Siebert, H.C.; Wilhelm, J.; Kaesser, U.; Dettmeyer, R.B.; Klein, H.; Ishaque,
    B.; et al. Articular Joint Lubricants during Osteoarthritis and Rheumatoid Arthritis Display Altered Levels and Molecular
    Species. PLoS ONE 2015, 10, e0125192, doi:10.1371/journal.pone.0125192.
  20. Oke, S.; Aghazadeh-Habashi, A.; Weese, J.S.; Jamali, F. Evaluation of glucosamine levels in commercial equine oral supplements
    for joints. Equine Vet. J. 2006, 38, 93–95, doi:10.2746/042516406775374306.
  21. Eckert, T.; Stötzel, S.; Burg-Roderfeld, M.; Sewing, J.; Lütteke, T.; Nifantiev, N.E.; Vliegenthart, J.F.G.; Siebert, H.-C. In silico
    Study on Sulfated and Non-Sulfated Carbohydrate Chains from Proteoglycans in Cnidaria and Interaction with Collagen. Open
    J. Phys. Chem. 2012, 2, 123–133, doi:10.4236/ojpc.2012.22017.
  22. Bhunia, A.; Vivekanandan, S.; Eckert, T.; Burg-Roderfeld, M.; Wechselberger, R.; Romanuka, J.; Bächle, D.; Kornilov, A.V.; von
    der Lieth, C.-W.; Jiménez-Barbero, J.S.; et al. Why Structurally Different Cyclic Peptides Can Be Glycomimetics of the HNK-1
    Carbohydrate Antigen. J. Am. Chem. Soc. 2010, 132, 96–105, doi:10.1021/ja100344v.
  23. Tsvetkov, Y.E.; Burg-Roderfeld, M.; Loers, G.; Arda, A.; Sukhova, E.V.; Khatuntseva, E.A.; Grachev, A.A.; Chizhov, A.O.; Siebert,
    H.C.; Schachner, M.; et al. Synthesis and molecular recognition studies of the HNK-1 trisaccharide and related oligosaccharides.
    The specificity of monoclonal anti-HNK-1 antibodies as assessed by surface plasmon resonance and STD NMR. J. Am. Chem.
    Soc. 2012, 134, 426–435, doi:10.1021/ja2083015.
  24. Toegel, S.; Pabst, M.; Wu, S.Q.; Grass, J.; Goldring, M.B.; Chiari, C.; Kolb, A.; Altmann, F.; Viernstein, H.; Unger, F.M. Phenotyperelated differential alpha-2,6- or alpha-2,3-sialylation of glycoprotein N-glycans in human chondrocytes. Osteoarthr. Cartil. 2010,
    18, 240–248, doi:10.1016/j.joca.2009.09.004.
  25. Schauer, R.; Kamerling, J.P. Exploration of the Sialic Acid World. Adv. Carb. Chem. Biochem. 2018, 75, 1–213,
    doi:10.1016/bs.accb.2018.09.001.
  26. Zhang, R.; Loers, G.; Schachner, M.; Boelens, R.; Wienk, H.; Siebert, S.; Eckert, T.; Kraan, S.; Rojas-Macias, M.A.; Lütteke, T.; et
    al. Molecular Basis of the Receptor Interactions of Polysialic Acid (polySia), polySia Mimetics, and Sulfated Polysaccharides.
    ChemMedChem 2016, 11, 990–1002, doi:10.1002/cmdc.201500609.
    Mar. Drugs 2021, 19, 542 29 of 30
  27. Siebert, H.-C.; Scheidig, A.; Eckert, T.; Wienk, H.; Boelens, R.; Mahvash, M.; Petridis, A.K.; Schauer, R. Interaction studies of
    sialic acids with model receptors contribute to nanomedical therapies. J. Neurol. Disord. 2015, 3, 1–6.
  28. Siebert, H.-C.; Lu, S.-Y.; Wechselberger, R.; Born, K.; Eckert, T.; Liang, S.; Lieth, C.-W.v.d.; Jiménez-Barbero, J.; Schauer, R.;
    Vliegenthart, J.F.G.; et al. A lectin from the Chinese bird-hunting spider binds sialic acids. Carbohydr. Res. 2010, 344, 1515–1525,
    doi:10.1016/j.carres.2009.06.002.
  29. Zhang, R.; Wu, L.; Eckert, T.; Burg-Roderfeld, M.; Rojas-Macias, M.A.; Lütteke, T.; Krylov, V.B.; Argunov, D.A.; Datta, A.;
    Markart, P.; et al. Lysozyme’s lectin-like characteristics facilitates its immune defense function. Q. Rev. Biophys. 2017, 50, e9,
    doi:10.1017/S0033583517000075.
  30. Zhang, R.; Eckert, T.; Lütteke, T.; Hanstein, S.; Scheidig, A.; Bonvin, A.M.; Nifantiev, N.E.; Kozar, T.; Schauer, R.; Enani, M.A.;
    et al. Structure-Function Relationships of Antimicrobial Peptides and Proteins with Respect to Contact Molecules on Pathogen
    Surfaces. Curr. Top. Med. Chem. 2016, 16, 89–98, doi:10.2174/1568026615666150703120753.
  31. Kar, R.K.; Gazova, Z.; Bednarikova, Z.; Mroue, K.H.; Ghosh, A.; Zhang, R.; Ulicna, K.; Siebert, H.C.; Nifantiev, N.E.; Bhunia, A.
    Evidence for Inhibition of Lysozyme Amyloid Fibrillization by Peptide Fragments from Human Lysozyme: A Combined
    Spectroscopy, Microscopy, and Docking Study. Biomacromolecules 2016, 17, 1998–2009, doi:10.1021/acs.biomac.6b00165.
  32. Oesser, S.; Adam, M.; Babel, W.; Seifert, J. Oral administration of (14)C labeled gelatin hydrolysate leads to an accumulation of
    radioactivity in cartilage of mice (C57/BL). J. Nutr. 1999, 129, 1891–1895, doi:10.1093/jn/129.10.1891.
  33. Oesser, S.; Seifert, J. Stimulation of type II collagen biosynthesis and secretion in bovine chondrocytes cultured with degraded
    collagen. Cell Tissue Res. 2003, 311, 393–399, doi:10.1007/s00441-003-0702-8.
  34. Schunck, M.; Louton, H.; Oesser, S. The Effectiveness of Specific Collagen Peptides on Osteoarthritis in Dogs-Impact on
    Metabolic Processes in Canine Chondrocytes. Open J. Anim. Sci. 2017, 07, 254–266, doi:10.4236/ojas.2017.73020.
  35. Dobenecker, B.; Reese, S.; Jahn, W.; Schunck, M.; Hugenberg, J.; Louton, H.; Oesser, S. Specific bioactive collagen peptides
    (PETAGILE((R))) as supplement for horses with osteoarthritis: A two-centred study. J. Anim. Physiol. Anim. Nutr. 2018, 102
    (Suppl. 1), 16–23, doi:10.1111/jpn.12863.
  36. Simons, V.S.; Lochnit, G.; Wilhelm, J.; Ishaque, B.; Rickert, M.; Steinmeyer, J. Comparative Analysis of Peptide Composition and
    Bioactivity of Different Collagen Hydrolysate Batches on Human Osteoarthritic Synoviocytes. Sci. Rep. 2018, 8, 17733,
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  37. Porfírio, E.; Fanaro, G.B. Collagen supplementation as a complementary therapy for the prevention and treatment of
    osteoporosis and osteoarthritis: A systematic review. Revista Brasileira de Geriatria e Gerontologia 2016, 19, 153–164,
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  38. Li, R.; Qiao, S.; Zhang, G. Analysis of angiotensin-converting enzyme 2 (ACE2) from different species sheds some light on crossspecies receptor usage of a novel coronavirus 2019-nCoV. J. Infect. 2020, 80, 469–496, doi:10.1016/j.jinf.2020.02.013.
  39. Saponaro, F.; Rutigliano, G.; Sestito, S.; Bandini, L.; Storti, B.; Bizzarri, R.; Zucchi, R. ACE2 in the Era of SARS-CoV-2:
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